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KMID : 0359920080270010055
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Korean Journal of Nephrology
2008 Volume.27 No. 1 p.55 ~ p.61
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Contrast-induced Nephropathy in Patients Undergoing Percutaneous Coronary Angiography and its Clinical Characteristics
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Choi Won
Lim Hyun-Min
Won Hye-Jin
Park Hye-Kyung
Lee Ban-Suck
Ahn Hyo-Seung
Ju Hye-Won
Kim Sang-Hyun
Park Won-Do
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Abstract
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Purpose: Contrast media-induced nephropathy (CIN) following coronary angiography is associated with an increased mortality and morbidity. We investigated the incidence of nephrotoxicity, clinical characteristics, laboratory characteristics and risk factors of CIN in patients undergoing coronary angiography.
Methods: We retrospectively evaluated the medical records of 555 patients who had undergone coronary angiography at the Sanggye Paik Hospital, from January 2004 to December 2005. We defined CIN as any increase in the creatinine value of more than 0.5 mg/dL or 50% of baseline value.
Result: Among 555 patients, CIN developed in 10 of 48 patients (20.8%) with renal insufficiency (serum creatinine ≥1.4 mg/dL) and in 7 of 507 patients (1.4%) without renal insufficiency (p<0.001). Decreased renal function, congestive heart failure, higher baseline uric acid, lower baseline albumin and age ≥65 years were the significant predictors of CIN. There were no statistical differences in contrast type and volume according to the development of CIN.
Conclusion: Our data supported the assumption that renal insufficiency, congestive heart failure, hyperuricemia and anemia may be the risk factors of developing CIN.
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KEYWORD
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Contrast media, Coronary angiography, Renal insufficiency, Uric acid
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